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Fundamental bioscience news

Scientists at TGAC have developed a new library construction method for genome sequencing that can simultaneously construct long-range data with reduced DNA input, time and cost. Long range genetic data (long mate pair – LMP) is an invaluable source for plant, crop and animal genetic research.

Neurons, the main functional units of our brain, develop as a result of coordinated activation of hundreds and possibly thousands of genes. Defects in this carefully orchestrated process often result in severe disorders such as neurodegenerative diseases or cancer.

A recent study by researchers at The Genome Analysis Centre (TGAC) and Jagiellonian University reveals a novel workflow, identifying associations between molecules to provide insights into cellular metabolism and gene expression in complex biological systems. This study has developed a unique bioinformatics approach for identifying associations between molecules from a range of vast data sources.